The second season of the mockumentary comedy series "St. Denis Medical" has premiered on November 3, 2025 on NBC, and is also streaming on Peacock. Created by Eric Ledgin and Justin Spitzer, the show stars Wendi McLendon-Covey, Allison Tolman, Josh Lawson, Mekki Leeper, Kahyun Kim, Kaliko Kauahi and David Alan Grier.
Find out more about the series after the jump.